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| Rodacki,M.; Zajdenverg,L.; Albernaz,M.S.; Bencke-Gonçalves,M.R.; Milech,A.; Oliveira,J.E.P.. |
| The objective of the present study was to determine whether the duration of disease has any influence on the prevalence of glutamic acid decarboxylase autoantibodies (GADA) in Brazilian patients with type 1 diabetes (T1D) and variable disease duration. We evaluated 83 patients with T1D. All participants were interviewed and blood was obtained for GADA measurement by a commercial radioimmunoassay (RSR Limited, Cardiff, UK). Four groups of patients were established according to disease duration: A) 1-5 years of disease (N = 24), B) 6-10 years of disease (N = 19), C) 11-15 years of disease (N = 25), and D) >15 years of disease (N = 15). GADA prevalence and its titers were determined in each group. GADA was positive in 38 patients (45.8%) and its frequency... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anti-GAD65 auto-antibodies; Type 1 diabetes mellitus; Time from diagnosis. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100008 |
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