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	Provedor de dados BABT (3) Autor Mohamed,Azza M (3) Abdelbaky,Nayira (2) Al-Rasheed,Nawal (2) Al-Rasheed,Nouf (2) Faddah,Laila (2) Al-Rasheed,Nawal M. (1) Al-Rasheed,Nouf M. (1) Attia,Hala A. (1) Fadda,Laila (1) Ibrahim,Hanan (1) Sharaf,Iman A (1) Mais... Palavra-chave Carnosine (2) Arginine (1) Carbon Tetrachloride (1) Cardiotoxicity (1) Curcumin (1) Hypoxia (1) Inflammatory molecules (1) Melatonin (1) Renal damage (1) Silymarin (1) Titanium dioxide nanoparticles (1) Vitamin E (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2016 (1) 2015 (2) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Assessment of the Potential Role of Silymarin Alone or in Combination with Vitamin E and/ or Curcumin on the Carbon Tetrachloride Induced Liver Injury in Rat BABT Al-Rasheed,Nouf; Faddah,Laila; Sharaf,Iman A; Mohamed,Azza M; Al-Rasheed,Nawal; Abdelbaky,Nayira. ABSTRACT The aim of this study was to investigate the effective role of silymarin either alone or in a combination with vitamin E and/or curcumin against the toxic impact of carbon tetrachloride (CCl4) induced liver injury The results revealed that administration of silymarin alone or in a combination with vitamin E and/or curcumin for 21 consecutive days, 24 h after CCl4 injection to rats, markedly ameliorated DNA damaged and apoptosis markers in rat livers, proinflammatory markers including tumor necrosis factor- α (TNF- α) and C-reactive protein (CRP ) in rat livers as well as interleukin 6 (IL-6), interferon gamma (IFN-γ) and vascular endothelial growth factor (VEGF) in rat sera. These treatments also could ameliorated the alteration in cytochrome P450... Tipo: Info:eu-repo/semantics/article Palavras-chave: Silymarin; Vitamin E; Curcumin; Carbon Tetrachloride. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000600833 Regulating Effect Of Carnosine And /Or L- Arginine On The Expression Of Inflammatory Molecules Induced Nephropathy In The Hypoxic Rat Model BABT Al-Rasheed,Nouf M.; Fadda,Laila; Mohamed,Azza M; Attia,Hala A.; Al-Rasheed,Nawal M.. This study aimed to explore the effective role of carnosine and /or L- arginine in down regulation of the inflammatory molecule expression caused renal damage in response to sodium nitrite (NaNO2) induced hypoxia in rats . NaNO2 was administered subcutaneously (s.c.) to rats as a single dose (60 mg/kg body weight ). L-arginine (200mg/Kg body weight) and carnosine (250 mg/ Kg body weight ) were administered (i.p.) as a single dose , 24 h before NaNO2 injection. The results revealed that pre- administration of arginine and /or carnosine to NaNO2 hypoxic rats, significantly modulated the increases in serum markers of renal function (creatinine and urea) as well as the decrease in hemoglobin (Hb) level versus hypoxic rats. The two agents each alone or in a... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypoxia; Arginine; Carnosine; Inflammatory molecules; Renal damage. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100310 Role of Carnosine and Melatonin in Ameliorating Cardiotoxicity of Titanium Dioxide Nanoparticles in the Rats BABT Al-Rasheed,Nouf; Faddah,Laila; Ibrahim,Hanan; Mohamed,Azza M; Al-Rasheed,Nawal; Abdelbaky,Nayira. The aim of this work was to study the possible cardiotoxicity of two different doses of 50 nm nano titanium dioxide (n-TiO2) and the possible modulating effects of the use of two natural antioxidants carnosine and melatonin. The results showed that TiO2- NPs produced deleterious effects on rat cardiac tissue as confirmed by the increased levels of serum myoglobin, troponin-T and CK-MB. Increased levels of serum Inflammatory markers represented by the tumor necrosis factor alpha (TNF-α) and Interleukin-6 (IL-6) was also noticed. Caspase3 and IGg were elevated compared to the control group in a dose dependant manner. treatment of the rats with Carnosine or melatonin. along with TiO2- NPs administration significantly improved most of the elevated biochemical... Tipo: Info:eu-repo/semantics/article Palavras-chave: Titanium dioxide nanoparticles; Cardiotoxicity; Carnosine; Melatonin. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400577 Registros recuperados: 3 Primeira ... 1 ... Última

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