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	Provedor de dados International Journal of Morphology (1) Autor Babakordi,F (1) Jahanshahi,M (1) Moharreri,A (1) Nickmahzar,E. G (1) Seif-hoseini,S (1) Palavra-chave Avoidance memory (1) Hippocampus (1) M1 receptor (1) Rat (1) Scopolamine (1) Tipo do documento Journal article (1) Ano 2013 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Scopolamine Reduces the Density of M1 Muscarinic Neurons in Rats' Hippocampus International Journal of Morphology Jahanshahi,M; Nickmahzar,E. G; Seif-hoseini,S; Babakordi,F; Moharreri,A. Cholinergic system in CNS is involved in learning and memory. Scopolamine as muscarinic acetylcholine receptor antagonist is used for creation of memory impairment. The purpose of this study is evaluation of scopolamine-based amnesia on memory retention and the effect of this phenomenon on the number of neurons contains M1-receptors in the male Wistar rats hippocampal regions. Thirty-five male Wistar rats (200±20 g) were distributed randomly into five groups. Control group (intact samples) and 3 experimental groups with sham group (saline) were tested by the method of passive avoidance (shuttle box) in doses of 0.2, 0.5 and 1 mg/kg (intraperitoneally) as a single dose. After one week, memory test was taken from the rats. Finally, brains dissected from... Tipo: Journal article Palavras-chave: M1 receptor; Scopolamine; Avoidance memory; Hippocampus; Rat. Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400014 Registros recuperados: 1 Primeira ... 1 ... Última

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