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González-Alvarez,Rafael; Garza-Rodriguez,María de Lourdes; Delgado-Enciso,Iván; Treviño-Alvarado,Victor Manuel; Canales-Del-Castillo,Ricardo; Martínez-De-Villarreal,Laura Elia; Lugo-Trampe,Ángel; Tejero,María Elizabeth; Schlabritz-Loutsevitch,Natalia E.; Rocha-Pizaña,María Del Refugio; Cole,Shelley A.; Reséndez-Pérez,Diana; Moises-Alvarez,Mario; Comuzzie,Anthony G.; Barrera-Saldaña,Hugo Alberto; Garza-Guajardo,Raquel; Barboza-Quintana,Oralia; Rodríguez-Sánchez,Irám Pablo. |
BACKGROUND: Chemerin, encoded by the retinoic acid receptor responder 2 (RARRES2) gene is an adipocytesecreted protein with autocrine/paracrine functions in adipose tissue, metabolism and inflammation with a recently described function in vascular tone regulation, liver, steatosis, etc. This molecule is believed to represent a critical endocrine signal linking obesity to diabetes. There are no data available regarding evolution of RARRES2 in non-human primates and great apes. Expression profile and orthology in RARRES2 genes are unknown aspects in the biology of this multigene family in primates. Thus; we attempt to describe expression profile and phylogenetic relationship as complementary knowledge in the function of this gene in primates. To do that, we... |
Tipo: Journal article |
Palavras-chave: Retinoic acid receptor; Responder protein; Primate; Chemerin; TIG2; Tazarotene-induced gene 2 protein; Gene expression. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100031 |
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