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Seroepidemiología y control de trichinellosis en cerdos en Sierra Grande, Argentina 78
Molina,V.; Albarracín,S.; Krivokapich,S.; Chiosso,C.; Mancini,S.; Bigatti,R.; Arbusti,P.; Avila,A.; Larrieu,E..
La zona de Sierra Grande, en la provincia de Río Negro, Argentina, se ha visto particularmente afectada por la trichinellosis, la cual sigue siendo endémica a nivel local. En el año 2000 fue diseñado un estudio descriptivo para conocer la historia natural de la trichinellosis en la zona. Durante el período 2001-2010 se llevó a cabo un programa de control en cerdos basado en la detección temprana de anticuerpos específicos mediante enzimoinmunoensayo (ELISA) con confirmación mediante Western blot y el sacrificio de los cerdos positivos. Así, el objetivo del presente trabajo fue evaluar los resultados del programa de control implementado en la reducción de la prevalencia de trichinellosis en cerdos en la localidad de Sierra Grande. Los primeros resultados...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Triquinosis; Trichinellosis; Control; Immunodiagnóstico; Seroepidemiología.
Ano: 2012 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982012000100004
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Effect of policosanol on cerebral ischemia in Mongolian gerbils 56
Molina,V.; Arruzazabala,M.L.; Carbajal,D.; Valdés,S.; Noa,M.; Más,R.; Fraga,V.; Menéndez,R..
Policosanol is a mixture of higher aliphatic primary alcohols isolated from sugar cane wax, whose main component is octacosanol. An inhibitory effect of policosanol on platelet aggregation and cerebral ischemia in animal models has been reported. Thus, the objective of the present study was to evaluate the effect of policosanol on cerebral ischemia induced by unilateral carotid ligation and bilateral clamping and recirculation in Mongolian gerbils. Policosanol (200 mg/kg) administered immediately after unilateral carotid ligation and at 12- or 24-h intervals for 48 h significantly inhibited mortality and clinical symptoms when compared with controls, whereas lower doses (100 mg/kg) were not effective. Control animals showed swelling (tissue vacuolization)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cerebral ischemia; Gerbils; Policosanol; Reperfusion brain edema.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001000014
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Protective effect of policosanol on atherosclerotic lesions in rabbits with exogenous hypercholesterolemia 56
Arruzazabala,M.L.; Noa,M.; Menéndez,R.; Más,R.; Carbajal,D.; Valdés,S.; Molina,V..
Policosanol is a mixture of higher aliphatic alcohols purified from sugar cane wax, with cholesterol-lowering effects demonstrable in experimental models and in patients with type II hypercholesterolemia. The protective effects of policosanol on atherosclerotic lesions experimentally induced by lipofundin in rabbits and rats and spontaneously developed in stumptail monkeys have been described. The present study was conducted to determine whether policosanol administered orally to rabbits with exogenous hypercholesterolemia also protects against the development of atherosclerotic lesions. Male New Zealand rabbits weighing 1.5 to 2 kg were randomly divided into three experimental groups which received 25 or 200 mg/kg policosanol (N = 7) orally for 60 days...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Policosanol; Atherosclerotic lesions; Exogenous hypercholesterolemia; Rabbits.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700015
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