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Genotypes and clinical data of respiratory syncytial virus and metapneumovirus in brazilian infants: a new perspective BJID
Riccetto,Adriana Gut Lopes; Silva,Luciana Helena Antoniassi da; Spilki,Fernando Rosado; Morcillo,André Moreno; Arns,Clarice Weis; Baracat,Emílio Carlos Elias.
The aim of this study was to determine if there was a correlation between respiratory syncytial virus (RSV) and metapneumovirus (MPV) genotypes and clinical data of Brazilian infants hospitalized for acute lower respiratory infection. The viruses in the patients' nasopharyngeal secretions were studied using the polymerase chain reaction and phylogenetic analysis. The study assessed 144 infants; 31.9% were RSV positive and 5.6% were MPV positive. Statistical analysis was performed using the chi-squared test, Fisher's test, Odds ratio, univariate logistic regression, non-conditional multivariate logistic regression and the forward - stepwise method. Multivariate analysis confirmed a significant relationship between a positive PCR test for RSV and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Respiratory syncytial virus; Metapneumovirus; Genotypes; Infants; Clinical.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000100008
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Usefulness of pharmacy dispensing records in the evaluation of adherence to antiretroviral therapy in Brazilian children and adolescents BJID
Ernesto,Aline Santarem; Lemos,Renata Muller Banzato Pinto de; Huehara,Maria Ivone; Morcillo,André Moreno; Vilela,Maria Marluce dos Santos; Silva,Marcos Tadeu Nolasco da.
INTRODUCTION: Adherence, which is crucial to the success of antiretroviral therapy (HAART), is currently a major challenge in the care of children and adolescents living with HIV/AIDS. OBJECTIVE: To evaluate the prevalence of nonadherence to HAART using complementary instruments in a cohort of children and adolescents with HIV/AIDS followed in a reference service in Campinas, Brazil. METHODS: The level of adherence of 108 patients and caregivers was evaluated by an adapted standardized questionnaire and pharmacy dispensing records (PDR). Non-adherence was defined as a drug intake lower than 95% (on 24-hour or seven-day questionnaires), or as an interval of 38 days or more for pharmacy refills. The association between adherence and clinical, immunological,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acquired immunodeficiency; Syndrome; Child; Adolescent; Highly active antiretroviral therapy; Medication adherence.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000400001
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Respiratory syncytial virus, infants and intensive therapy BJID
Bueno,Ieda Aparecida Correa; Riccetto,Adriana Gut Lopes; Morcillo,André Moreno; Arns,Clarice Weis; Baracat,Emílio Carlos Elias.
The aims of this study were to determine the presence of respiratory syncytial virus (RSV) and to assess the clinical features of the disease in infants with acute low respiratory tract infection hospitalized at pediatric intensive care units (PICU) of two university teaching hospitals in São Paulo State, Brazil. Nasopharyngeal secretions were tested for the RSV by the polymerase chain reaction. Positive and negative groups for the virus were compared in terms of evolution under intensive care (mechanical pulmonary ventilation, medications, invasive procedures, complications and case fatality). Statistical analysis was performed using the Mann Whitney and Fisher's exact tests. A total of 21 infants were assessed, 8 (38.1%) of whom were positive for RSV....
Tipo: Info:eu-repo/semantics/other Palavras-chave: Respiratory syncytial virus; Infants; Intensive therapy; Genotypes.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100016
Registros recuperados: 3
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