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Azole resistance in Candida spp. isolated from Catú Lake, Ceará, Brazil: an efflux-pump-mediated mechanism BJM
Brilhante,Raimunda S.N.; Paiva,Manoel A.N.; Sampaio,Célia M.S.; Castelo-Branco,Débora S.C.M.; Teixeira,Carlos E.C.; Alencar,Lucas P. de; Bandeira,Tereza J.P.G.; Monteiro,André J.; Cordeiro,Rossana A.; Pereira-Neto,Waldemiro A.; Sidrim,José J.C.; Moreira,José L.B.; Rocha,Marcos F.G..
Abstract Since, there is no study reporting the mechanism of azole resistance among yeasts isolated from aquatic environments; the present study aims to investigate the occurrence of antifungal resistance among yeasts isolated from an aquatic environment, and assess the efflux-pump activity of the azole-resistant strains to better understand the mechanism of resistance for this group of drugs. For this purpose, monthly water and sediment samples were collected from Catú Lake, Ceará, Brazil, from March 2011 to February 2012. The obtained yeasts were identified based on morphological and biochemical characteristics. Of the 46 isolates, 37 were Candida spp., 4 were Trichosporon asahii, 3 were Cryptococcus laurentii, 1 Rhodotorula mucilaginosa, and 1 was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aquatic environments; Yeast microbiota; Candida spp.; Antifungal resistance.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000100033
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Viral Hepatitis C in a leading Brazilian hospital: epidemiological factors and genotyping BJM
Bezerra,Cristianne S.; Lima,José M.C.; Vilar,Janaina L.; Moreira,José L.B.; Frota,Cristiane C..
The hepatitis C virus (HCV) is classified into six different genotypes and their distribution is different throughout the world. Epidemiologic studies are important to determine several characteristics of the virus, as well as the disease. This study analysed the prevalence of HCV and its genotypes among patients from a leading hospital in Ceará, which is located in Northeast Brazil. A total of 119 anti-HCV-seropositive patients, each having previously completed a questionnaire about risk behaviours related to HCV infection were tested for HCV infection using a qualitative HCV polymerase chain reaction (PCR) assay and genotyping by restriction fragment length polymorphism (RFLP). The detection was based on amplifying of the non-coding 5' region. Of the 119...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C virus; Genotypes; Epidemiology; Northeast Brazil; Viral hepatitis.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000400014
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