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| Luiz,Roberta dos Santos Silva; Suffys,Phillip; Barroso,Elizabeth Clara; Kerr,Ligia Regina Franco Sansigolo; Duarte,Cynthia Romariz; Freitas,Max Victor Carioca; Mota,Rosa Maria Salani; Frota,Cristiane Cunha. |
| OBJECTIVES: This study has used a combination of clinical information, spoligotyping, and georeferencing system to elucidate the genetic diversity of the Mycobacterium tuberculosis isolates circulating in a TB-prevalent municipality of Northeast Brazil. METHODS: A total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in Fortaleza. Drug susceptibility and spoligotyping assays were performed and place of residence of the patients were georeferenced. RESULTS: Of the M. tuberculosis strains studied, 51 (44.3%) isolates were resistant to at least one drug (R-TB) and 64 (55.7%) were sensitive to all the drugs tested (S-TB). A high frequency of resistance was found in previously treated cases (84%)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tuberculosis; Drug-resistant tuberculosis; Georeferencing; Spoligotyping. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300006 |
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