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	Provedor de dados BJPS (1) Autor Kumar,Kommana Srinivas Phani (1) Murthy,Kolaplli Venkata Ramana (1) Rao,Nali Sreenivasa (1) Srikanth,Meka Venkata (1) Sunil,Songa Ambedkar (1) Uhumwangho,Michael Uwumagbe (1) Mais... Palavra-chave Chronotherapeutic drug/delivery systems (1) Compression coated tablets (1) Polyethylene Oxides (1) Predetermined lag time (1) Torsemide (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2011 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Development and evaluation of a chronotherapeutic drug delivery system of torsemide BJPS Sunil,Songa Ambedkar; Rao,Nali Sreenivasa; Srikanth,Meka Venkata; Uhumwangho,Michael Uwumagbe; Kumar,Kommana Srinivas Phani; Murthy,Kolaplli Venkata Ramana. The objective of this study was to prepare and evaluate chronotherapeutic drug delivery systems (ChrDDs) of torsemide. Compression coated tablets (CCT) containing torsemide in the core tablet were prepared by the compression coating technique with different grades of polyethylene oxide (PEO WSR 301 &amp; 1105). The optimized formulations were characterised for tabletting parameters and drug polymer interaction by Fourier-Transform Infrared Spectroscopy (FTIR).The hardness of all the CCT using PEO WSR 301 &amp; PEO WSR 1105 were in the range 6-8 kg/cm² &amp; 5.5 to 7 kg/cm² respectively. Their friability values were <0.3%. All the CCT showed a clear lag time but finalized as per the predetermined lag time. As the amount of PEO was increased... Tipo: Info:eu-repo/semantics/article Palavras-chave: Torsemide; Chronotherapeutic drug/delivery systems; Polyethylene Oxides; Compression coated tablets; Predetermined lag time. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300017 Registros recuperados: 1 Primeira ... 1 ... Última

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