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	Provedor de dados BJMBR (1) Autor Boichot,E. (1) Lagente,V. (1) Le Quément,C. (1) Manoury,B. (1) Martin-Chouly,C. (1) Nénan,S. (1) Mais... Palavra-chave Chronic obstructive pulmonary disease (1) Fibrosis (1) Inflammation (1) Lung (1) Matrix metalloproteinase (1) Tissue inhibitor of matrix metalloproteinases (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2005 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Role of matrix metalloproteinases in the development of airway inflammation and remodeling BJMBR Lagente,V.; Manoury,B.; Nénan,S.; Le Quément,C.; Martin-Chouly,C.; Boichot,E.. Matrix metalloproteinases (MMPs) are a major group of proteases known to regulate extracellular matrix (ECM) turnover and so they have been suggested to be important in the process of lung disease associated with tissue remodeling. This has led to the concept that modulation of airway remodeling including excessive proteolysis damage to the tissue may be of interest for future treatment. Within the MMP family, macrophage elastase (MMP-12) is able to degrade ECM components such as elastin and is involved in tissue remodeling processes in chronic obstructive pulmonary disease including emphysema. Pulmonary fibrosis has an aggressive course and is usually fatal within an average of 3 to 6 years after the onset of symptoms. Pulmonary fibrosis is associated... Tipo: Info:eu-repo/semantics/article Palavras-chave: Fibrosis; Inflammation; Lung; Matrix metalloproteinase; Tissue inhibitor of matrix metalloproteinases; Chronic obstructive pulmonary disease. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000009 Registros recuperados: 1 Primeira ... 1 ... Última

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