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	Provedor de dados BJMBR (1) Autor Bazotte,R.B. (1) Curi,R. (1) Lima,F.B. (1) Lopes,G. (1) Nakano,L.C. (1) Vardanega-Peicher,M. (1) Mais... Palavra-chave Adrenergic responsiveness (1) Glycogenolysis (1) Hepatic glucose production (1) Hypoglycemia (1) Insulin-induced hypoglycemia (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2000 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Time sequence of changes in the responsiveness of glycogen breakdown to adrenergic agonists in perfused liver of rats with insulin-induced hypoglycemia BJMBR Vardanega-Peicher,M.; Lopes,G.; Lima,F.B.; Curi,R.; Nakano,L.C.; Bazotte,R.B.. The time-course changes of the responsiveness of glycogen breakdown to a- and ß-adrenergic agonists during insulin-induced hypoglycemia (IIH) were investigated. Blood glucose levels were decreased prior to the alteration in the hepatic responsiveness to adrenergic agonists. The activation of hepatic glucose production and glycogenolysis by phenylephrine (2 µM) and isoproterenol (20 µM) was decreased in IIH. The changes in the responsiveness of glycogen catabolism were first observed for isoproterenol and later for phenylephrine. Hepatic ß-adrenergic receptors showed a higher degree of adrenergic desensitization than did a-receptors. Liver glycogen synthase activity, glycogen content and the catabolic effect of dibutyryl cyclic AMP (the ß-receptor second... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypoglycemia; Adrenergic responsiveness; Insulin-induced hypoglycemia; Hepatic glucose production; Glycogenolysis. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700011 Registros recuperados: 1 Primeira ... 1 ... Última

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