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Expression of uterine lipocalin 2 and its receptor during early- to mid-pregnancy period in mares OAK
Haneda, Shingo; Nagaoka, Kentaro; Nambo, Yasuo; Kikuchi, Masato; Nakano, Yasuko; Li, Junyou; Matsui, Motozumi; Miyake, Yo-ichi; Imakawa, Kazuhiko.
From previous cDNA subtraction studies analyzing gene expression in equine endometrium, high lipocalin 2 (LCN2) mRNA expression was found in the gravid endometrium. In the uterus, LCN2 may transport hydrophobic molecules and siderophores with iron, or may form a complex with another protein, however, the expression of uterine LCN2 beyond day 20 of equine pregnancy and its receptor has not been characterized. To study the expression and potential roles of uterine LCN2 from pre-implantation to mid-gestation period, stage-specific endometrial samples were obtained from day 13 (day 0 = ovulation) cyclic and days 13, 19, 25, and 60 to 131 pregnant mares. Expression of LCN2 mRNA increased in day 19 gravid endometrium and was abundant from day 60 onward. The...
Palavras-chave: Endometrium; Equine; Lipocalin 2 (LCN2); LCN2 receptor (SLC22A17); Matrix metalloproteinase-9 (MMP9).
Ano: 2017 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4424
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Effects of dystocia on blood gas parameters, acid-base balance and serum lactate concentration in heavy draft newborn foals OAK
Kimura, Yuki; Aoki, Takahiro; Chiba, Akiko; Nambo, Yasuo.
Dystocia is often lethal for neonatal foals; however, its clinicopathological features remain largely unknown. We investigated the effect of dystocia on the foal blood profile. Venous blood samples were collected from 35 foals (5 Percheron and 30 crossbreds between Percheron, Belgian, and Breton heavy draft horses) at 0 hr, 1 hr, 12 hr and 1 day after birth. Dystocia was defined as prolonged labor >30 min with strong fetal traction with or without fetal displacement. The dystocia group (n=13) showed lower mean values for pH (P<0.01), bicarbonate (P<0.01), total carbon dioxide (P<0.05), and base excess (P<0.01) and higher mean values for anion gap (P<0.05) and lactate (P<0.01) immediately after birth than the normal group (n=22)....
Palavras-chave: Dystocia; Heavy draft horse; Lactic acidosis; Neonatal foal; PH.
Ano: 2017 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4533
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