|
|
|
|
|
| Ortiz-Covarrubias,Alejandro; Fang,Edward; Prokocimer,Philippe G.; Flanagan,Shawn D.; Zhu,Xu; Cabré-Márquez,Jose Francisco; Tanaka,Toshiaki; Passarell,Julie; Fiedler-Kelly,Jill; Nannini,Esteban C.. |
| Abstract Acute bacterial skin and skin structure infections are caused mainly by Gram-positive bacteria which are often treated with intravenous vancomycin, daptomycin, or linezolid, with potential step down to oral linezolid for outpatients. Tedizolid phosphate 200 mg once daily treatment for six days demonstrated non-inferior efficacy, with a favourable safety profile, compared with linezolid 600 mg twice daily treatment for 10 days in the Phase 3 ESTABLISH-1 and -2 trials. The objective of the current post-hoc analysis of the integrated dataset of ESTABLISH-1 and -2 was to evaluate the efficacy and safety of tedizolid (N = 182) vs linezolid (N = 171) in patients of Latino origin enrolled into these trials. The baseline demographic characteristics of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ABSSSI; Latino ethnicity; Oxazolidinone; Tedizolid. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000200184 |
| |
|
|
| Nannini,Esteban C.; Ponessa,Adriana; Muratori,Rosa; Marchiaro,Patricia; Ballerini,Viviana; Flynn,Luis; Limansky,Adriana S.. |
| ABSTRACTA nosocomial polyclonal outbreak associated to bacteremia caused by differentBurkholderia cepacia complex (BCC) species and clones is reported. Molecular characterization identified Burkholderia stabilis, Burkholderia contaminans, and Burkholderia ambifaria among BCC isolates obtained from patients in neonatal and adult intensive care units. BCC was also isolated from an intrinsically contaminated ultrasound gel, which constituted the presumptive BCC source. Prior BCC outbreak related to contaminated ultrasound gels have been described in the setting of transrectal prostate biopsy. Outbreak caused strains and/or clones of BCC have been reported, probably because BCC are commonly found in the natural environment; most BCC species are biofilm... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Burkholderia cepacia complex; Outbreak; Bacteremia; Polyclonal. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000500543 |
| |
|
|
|
