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| Zaladek-Gil,F.; Cavanal,M.F.; Nascimento-Gomes,G.; Silva-Rocha,M.C.; Nutti-de-Almeida,M.. |
| In previous studies we have shown stimulation of renal acid excretion in the proximal tubules of rats with diabetes of short duration, with no important alterations in glomerular hemodynamics; on the other hand, in thyroparathyroidectomized rats (TPTX model), a significant decrease in renal acid excretion, glomerular filtration rate (GFR) and renal plasma flow (RPF) was detected. Since important changes in the parathyroid hormone-vitamin D-Ca axis are observed in the diabetic state, the present study was undertaken to investigate the renal repercussions of thyroparathyroidectomy in rats previously made diabetic by streptozotocin (45 mg/kg). Four to 6 days after the induction of diabetes (DM), a group of rats were thyroparathyroidectomized (DM + TPTX).... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diabetes; Thyroparathyroidectomy; Renal function; Acid excretion. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100016 |
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