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Prolactin induces adrenal hypertrophy BJMBR
Silva,E.J.; Felicio,L.F.; Nasello,A.G.; Zaidan-Dagli,M.; Anselmo-Franci,J.A..
Although adrenocorticotropic hormone is generally considered to play a major role in the regulation of adrenal glucocorticoid secretion, several reports have suggested that other pituitary hormones (e.g., prolactin) also play a significant role in the regulation of adrenal function. The aim of the present study was to measure the adrenocortical cell area and to determine the effects of the transition from the prepubertal to the postpubertal period on the hyperprolactinemic state induced by domperidone (4.0 mg kg-1 day-1, sc). In hyperprolactinemic adult and young rats, the adrenals were heavier, as determined at necropsy, than in the respective controls: adults (30 days: 0.16 ± 0.008 and 0.11 ± 0.007; 46 days: 0.17 ± 0.006 and 0.12 ± 0.008, and 61 days:...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pituitary; Domperidone; Dopamine; Rats; Morphometry.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000200005
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The brain decade in debate: VIII. Peptide hormones and behavior: cholecystokinin and prolactin BJMBR
Beinfeld,M.C.; Bittencourt,J.C.; Bridges,R.S.; Faris,P.L.; Lucion,A.B.; Nasello,A.G.; Weller,A.; Felicio,L.F..
This article is a transcription of an electronic symposium held on November 28, 2000 in which active researchers were invited by the Brazilian Society of Neuroscience and Behavior (SBNeC) to discuss the advances of the last decade in the peptide field with particular focus on central actions of prolactin and cholecystokinin. The comments in this symposium reflect the diversity of prolactin and cholecystokinin research and demonstrate how the field has matured. Since both peptides play a role in reproductive behaviors, particularly mother-infant interactions, this was the starting point of the discussion. Recent findings on the role of the receptor subtypes as well as interaction with other peptides in this context were also discussed. Another issue...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CCK; PRL; Dopamine; Maternal behavior; Bulimia; Motivation.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001100002
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