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Cell proliferation of the ileum intestinal mucosa of diabetic rats treated with ascorbic acid Biocell
Nelisis Zanoni,Jacqueline; Fernandes Pereira,Renata Virginia.
The objective of this work was to evaluate the effect of the ascorbic acid supplementation on the cellular proliferation on the ileum mucosa of diabetic rats. Fifteen 90-days rats were divided in the groups: control, diabetic and diabetic supplemented with ascorbic acid (DA). Two hours prior the sacrifice, they were injected with Vincristin. Semi-seriate histological cuts stained with HE were accomplished. About 2500 crypt cells from the intestinal mucosa were counted in order to obtain the metaphasic indexes. The height and depth of 30 villi and 30 crypts were measured for each animal, respectively. The metaphasic indexes showed no significant changes when we compared the three groups: 20.2 ± 0.7 (control), 18 ± 1.9 (diabetic) and 17 ± 1.4 (DA) (p >...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ascorbic acid; Diabetes mellitus; Lleum; Cellular proliferation.
Ano: 2008 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452008000200001
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Creatine supplementation in trained rats causes changes in myenteric neurons and intestinal wall morphometry Biocell
Franzói De Moraes,Solange Marta; Brogio,Thais Andréia; Nelisis Zanoni,Jacqueline; Vicente Umada Zapater,Mariana Cristina; Barnabé Peres,Sidney; Hernandes,Luzmarina.
Creatine is widely used by athletes as an ergogenic resource. The aim of this study was to evaluate the influence of creatine supplementation on the duodenum of rats submitted to physical training. The number and myenteric neuronal cell bodies as well mucosal and muscular tunic morphometry were evaluated. Control animals received a standard chow for 8 weeks, and the treated ones received the standard chow for 4 weeks and were later fed with the same chow but added with 2% creatine. Animals were divided in groups: sedentary, sedentary supplemented with creatine, trained and trained supplemented with creatine. The training consisted in treadmill running for 8 weeks. Duodenal samples were either processed for whole mount preparations or for paraffin embedding...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nutritional supplementation; Duodenum; Exercise.
Ano: 2013 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452013000200004
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