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Nicastro,H.; Zanchi,N.E.; da Luz,C.R.; Lancha Jr.,A.H.. |
Abstract The reduction of skeletal muscle loss in pathological states, such as muscle disuse, has considerable effects in terms of rehabilitation and quality of life. Since there is no currently effective and safe treatment available for skeletal muscle atrophy, the search for new alternatives is necessary. Resistance exercise (RE) seems to be an important tool in the treatment of disuse-induced skeletal muscle atrophy by promoting positive functional (strength and power) and structural (hypertrophy and phenotypic changes) adaptive responses. Human and animal studies using different types of resistance exercise (flywheel, vascular occlusion, dynamic, isometric, and eccentric) have obtained results of great importance. However, since RE is a complex... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Resistance exercise; Vascular occlusion; Eccentric exercise; Disuse; Atrophy. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001100001 |
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Carnevali Jr,L.C.; Eder,R.; Lira,F.S.; Lima,W.P.; Gonçalves,D.C.; Zanchi,N.E.; Nicastro,H.; Lavoie,J.M.; Seelaender,M.C.L.. |
We examined the capacity of high-intensity intermittent training (HI-IT) to facilitate the delivery of lipids to enzymes responsible for oxidation, a task performed by the carnitine palmitoyl transferase (CPT) system in the rat gastrocnemius muscle. Male adult Wistar rats (160-250 g) were randomly distributed into 3 groups: sedentary (Sed, N = 5), HI-IT (N = 10), and moderate-intensity continuous training (MI-CT, N = 10). The trained groups were exercised for 8 weeks with a 10% (HI-IT) and a 5% (MI-CT) overload. The HI-IT group presented 11.8% decreased weight gain compared to the Sed group. The maximal activities of CPT-I, CPT-II, and citrate synthase were all increased in the HI-IT group compared to the Sed group (P < 0.01), as also was gene... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: High-intensity intermittent training; Lipid metabolism; Carnitine palmitoyl transferase. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000800013 |
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