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| Rosa,Roseane Leandra da; Nardi,Geisson Marcos; Januário,Adriana Graziele de Farias; Boçois,Renata; Bagatini,Katiane Paula; Bonatto,Sandro José Ribeiro; Pinto,Andrea de Oliveira; Ferreira,João Ronaldo Notargiacomo; Mariano,Luisa Nathália Bolda; Niero,Rivaldo; Iagher,Fabíola. |
| Luehea divaricata (Malvaceae) is a plant widely used for treatment of various inflammatory and infectious conditions; however few reports discuss its biological properties. The aim of this study was to evaluate the anti-inflammatory and analgesic effects as well as the macrophage activity in mice treated with the hydroalcoholic crude extract of L. divaricata(CLD). Thin layer chromatography revealed presence of epicathequin, stigmasterol, lupeol and α,β-amyrin in the extract. To evaluate the anti-inflammatory and analgesic activities, animals were subjected to paw edema induced by carrageenan test, writhing, formalin and capsaicin tests. Immunomodulatory activity was evaluated by adhesion and phagocytic capacity, lysosomal volume, and reactive oxygen... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Luehea divaricata Mart. & Zucc./pharmacognosy Luehea divaricata Mart. & Zucc./hydroalcoholic crude extract/properties Anti-inflammatories Analgesics Reactive oxygen species. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300599 |
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| Zandonai,Rodrigo Hermes; Coelho,Fabiana; Ferreira,Juliana; Mendes,Ana Karla Bittencourt; Biavatti,Maique Weber; Niero,Rivaldo; Cechinel Filho,Valdir; Bueno,Ednéia Casagranda. |
| A number of natural compounds have been used as immunomodulatory agents, enabling the function of the immune system to be modified by stimulating or suppressing it. There has been increasing interest in the study of therapeutic action of plant extracts regarding their immunomodulatory activity. The aim of this study was to identify and evaluate the action of extracts of the medicinal plants Calophyllum brasiliense, Ipomoea pes-caprae, Matayba elaeagnoides, Maytenus robusta, Rubus imperialis and Vernonia scorpioides on the development of spleen cells from mice, using the in vitro cellular proliferation assay. The cells, obtained by mechanical rupture of mice spleen (5x10(4) cells/mL), were incubated with methanol extracts (10, 50, 100 and 200 µg/mL) and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Medicinal plants; Natural products/immunomodulatories; Immunomodulation; Calophyllum brasiliense/pharmacognosy; Ipomoea pes-caprae/pharmacognosy; Matayba elaeagnoides/pharmacognosy; Maytenus robusta/pharmacognosy; Rubus imperialis/pharmacognosy; Vernonia scorpioides/pharmacognosy. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200020 |
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| Scapinello,Jaqueline; Oliveira,José V. de; Chiaradia,Luis A.; Tomazelli Junior,Osmar; Niero,Rivaldo; Dal Magro,Jacir. |
| This study evaluates the effects of supercritical carbon dioxide extracts obtained from the fruit of Melia azedarach L. (Meliaceae) on the development of Spodoptera frugiperda J.E. Smith, 1797 (Lepidoptera: Noctuidae), from the larval period until the insect adulthood. For this purpose, a laboratory-scale extraction unit was operated at 60 °C and 200 bar. Larval mortality increased by raising the extract concentration tested: the value of LC50 calculated by Probit analysis was 376.74 mg kg-1, and at a concentration of 5000 mg kg-1, the mortality was 100%. The extract exhibited insect growth inhibitory activity in the higher concentrations (500 mg kg-1, 1000 mg kg-1 and 5000 mg kg-1), due to antifeedant action, resulting in larvae and pupae with mass and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Supercritical extraction; Fall armyworm; Chinaberry. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-43662014000800014 |
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