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Isolation of Sporothrix schenkii from the nails of healthy cats BJM
Souza,Lorena Leonardo de; Nascente,Patrícia da Silva; Nobre,Márcia Oliveira; Meinerz,Ana Raquel Mano; Meireles,Mário Carlos Araújo.
Many cases of sporotrichosis in cats were diagnosed in the town of Rio Grande, RS, Brazil, caused mainly by inoculation due to scratches. In this work, we evaluated the frequency of Sporothrix schenckii in the nails of healthy cats living together with cats showing clinical sporotrichosis. The isolation of the fungus was carried out pressing unwashed nails of the forelimbs of 24 cats (48 paws) directly onto the surface of Mycobiotic Agar in Petri dishes. S. schenckii was isolated from seven (29.1%) cats. The procedure for isolation of the fungus was simpler than methods that require sedation and cuts of the nails.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Sporotrichosis; Cats; Nails; Sporothrium schenckii.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000300031
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Efficacy of terbinafine and itraconazole on a experimental model of systemic sporotrichosis BJM
Meinerz,Ana Raquel Mano; Xavier,Melissa O.; Cleff,Marlete Brum; Madrid,Isabel Martins; Nobre,Márcia Oliveira; Meireles,Mário Carlos Araújo; Mello,João Roberto Braga de.
Itraconazole is currently considered the drug of choice to treat the diverse clinical presentation of sporotrichosis. On the other hand terbinafine by virtue of its excellent in vitro activity is under comparative evaluation for its therapeutic potential for a wide range of fungal infections. In this study, our aim was to determine the in vivo efficacy of terbinafine and itraconazole on a experimental model of systemic sporotrichosis. 120 rats Wistar received an injection of 2x10³ S. schenckii cells by via the lateral tail vein. After 3 days the animals were treated with terbinafine (250mg/kg) and itraconazole (100 mg/kg) and their respective diluents. In our model, terbinafine and itraconazole were effective in reducing the number of clinical lesions and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Itraconazole; Terbinafine; Sporotrichosis; Antifungal.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000400025
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