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Incidence of Trypanosoma cruzi transmission through breastfeeding during acute experimental Chagas disease BJID
Martins,Luciamare Perinetti Alves; Castanho,Roberto Esteves Pires; Nogueira,Adriano Barbosa; Silva,Otavio Turolo da; Gusmão,Alex Silva de.
OBJECTIVE: To verify the incidence of T. cruzi transmission through breastfeeding during acute experimental Chagas' disease. METHODS: Fifteen female Swiss mice were mated and, after pregnancy confirmation, placed in individual cages. A few hours after birth, the females were inoculated with 0.1 mL of blood containing approximately 3 x 10(5) trypomastigote forms of Y strain of T. cruzi and continued breastfeeding for 25 days. RESULTS: In 142 offspring examined no infection through breast-feeding was observed. CONCLUSIONS: The low number of trypomastigote forms ingested by the newborn mice combined with biological and biochemical characteristics of blood trypomastigotes may explain the lack of transmission in this experiment.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Trypanosoma cruzi; Foods for pregnant and breastfeeding mothers; Chagas disease.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000200004
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