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Phylodynamics and human-mediated dispersal of a zoonotic virus. ArchiMer
Talbi, Chiraz; Lemey, Philippe; Suchard, Marc A.; Abdelatif, Elbia; Elharrak, Mehdi; Nourlil, Jalal; Abdellah, Faouzi; Echevarria, Juan E.; Moron, Sonia Vasquez; Rambaut, Andrew; Campiz, Nicholas; Tatem, Andrew J.; Holmes, Edward; Bourhy, Hervé.
Understanding the role of humans in the dispersal of predominately animal pathogens is essential for their control. We used newly developed Bayesian phylogeographic methods to unravel the dynamics and determinants of the spread of dog rabies virus (RABV) in North Africa. Each of the countries studied exhibited largely disconnected spatial dynamics with major geo-political boundaries acting as barriers to gene flow. Road distances proved to be better predictors of the movement of dog RABV than accessibility or raw geographical distance, with occasional long distance and rapid spread within each of these countries. Using simulations that bridge phylodynamics and spatial epidemiology, we demonstrate that the contemporary viral distribution extends beyond that...
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Ano: 2010 URL: http://archimer.ifremer.fr/doc/00139/24992/23090.pdf
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Norovirus and Other Human Enteric Viruses in Moroccan Shellfish ArchiMer
Benabbes, Laila; Ollivier, Joanna; Schaeffer, Julien; Parnaudeau, Sylvain; Rhaissi, Houria; Nourlil, Jalal; Le Guyader, Soizick.
The aim of this study was to evaluate the presence of human enteric viruses in shellfish collected along the Mediterranean Sea and Atlantic Coast of Morocco. A total of 77 samples were collected from areas potentially contaminated by human sewage. Noroviruses were detected in 30 % of samples, with an equal representation of GI and GII strains, but were much more frequently found in cockles or clams than in oysters. The method used, including extraction efficiency controls, allowed the quantification of virus concentration. As in previous reports, results showed levels of contamination between 100 and 1,000 copies/g of digestive tissues. Sapoviruses were detected in 13 % of samples mainly in oyster and clam samples. Hepatitis A virus was detected in two...
Tipo: Text Palavras-chave: Shellfish; Norovirus; Hepatitis A virus; Environmental conditions; Quantification; Morocco.
Ano: 2013 URL: http://archimer.ifremer.fr/doc/00130/24102/22489.pdf
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