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Artemisia annua increases resistance to heat and oxidative stresses, but has no effect on lifespan in Caenorhabditis elegans Ciênc. Tecnol. Aliment.
OH,Seung-Il; KIM,Jun-Sung; KIM,Chul-Kyu; YI,Sun Shin; KIM,Sung-Jo; PARK,Sang-Kyu.
Abstract It is suggested that oxidative stress induced by cellular reactive oxygen species is one of the major causal factors of aging. The effect of dietary supplementation of anti-oxidants on response to environmental stressors and lifespan has been studied in various model organisms. In the present study, we examine the effect of Artemisia annua extract on resistance to oxidative, heat, and ultraviolet stresses in the nematode Caenorhabditis elegans. Artemisia annua significantly increases survival under oxidative and heat stresses, however has no effects in response to ultraviolet stress. Then, we measured the in vivo changes in expression of stress-responsive genes by Artemisia annua using green fluorescence protein. The expression of hsp-16.2, known...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Artemisia annua; Oxidative stress; Heat stress; Lifespan; C. elegans.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612016000200356
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