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	Provedor de dados Biol. Res. (2) Autor OKOH,ANTHONY I (2) AFOLAYAN,ANTHONY J (1) AIYEGORO,AYOBAMI O (1) AIYEGORO,OLAYINKA A (1) AKINPELU,DAVID A (1) Palavra-chave Afzelia africana (1) Antibacteria (1) Helichrysum pedunculatum (1) Killing rate (1) Phytochemistry (1) Protein leakage (1) Synergism (1) Time kill assay (1) Mais... Tipo do documento Journal article (2) Ano 2009 (2) País Chile (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Studies on the biocidal and cell membrane disruption potentials of stem bark extracts of Afzelia africana (Smith) Biol. Res. AKINPELU,DAVID A; AIYEGORO,AYOBAMI O; OKOH,ANTHONY I. We had recently reported antibacterial activity in the crude extract of the stem bark of Afzelia africana (Akinpelu et al., 2008). In this study, we assessed the biocidal and cell membrane disruption potentials of fractions obtained from the crude extract of the plant. The aqueous (AQ) and butanol (BL) fractions exhibited appreciable antibacterial activities against the test bacteria. The minimum inhibitory concentrations of the AQ and BL fractions ranged between 0.313 and 2.5 mg/ml, while their minimum bactericidal concentrations varied between 0.625 and 5.0 mg/ml. Also, the AQ fraction killed about 95.8% of E. coli cells within 105 min at a concentration of 5 mg/ml, while about 99.1% of Bacillus pumilus cells were killed by this fraction at the same... Tipo: Journal article Palavras-chave: Afzelia africana; Antibacteria; Phytochemistry; Killing rate; Protein leakage. Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300008 Synergistic interaction of Helichrysum pedunculatum leaf extracts with antibiotics against wound infection associated bacteria Biol. Res. AIYEGORO,OLAYINKA A; AFOLAYAN,ANTHONY J; OKOH,ANTHONY I. The effect of combinations of the crude methanolic extract of the leaves of Helichrysum pedunculatum and eight first-line antibiotics were investigated by time kill assays against a panel of bacterial strains that have been implicated in wound infections. The plant extract showed appreciable antibacterial activities against the test bacteria with zones of inhibition ranging between 18 and 27 mm, and minimum inhibitory concentrations (MICs) varying between 0.1 and 5.0 mg/ml. The MICs of the test antibiotics range between 0.001 and 0.412 mg/ml, and combination of the plant extract and the antibiotics resulted in reduction of bacterial counts by between 0 and 6.63 Log10 cfu/ml. At V2 MIC, 56.81% synergy; 43.19% indifference and no antagonism were observed,... Tipo: Journal article Palavras-chave: Helichrysum pedunculatum; Time kill assay; Synergism. Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300007 Registros recuperados: 2 Primeira ... 1 ... Última

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