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| OLIVEIRA,SIMONE Q.; KRATZ,JADEL M.; CHAVES,VITOR C.; GUIMARÃES,TATIANA R.; COSTA,DANIELLE T.M.; DIMITRAKOUDI,SAPFO; VONTZALIDOU,ARGYRO; BORDIGNON,SÉRGIO A.L.; SIMIONATO,CESAR P.; STEINDEL,MÁRIO; REGINATTO,FLÁVIO H.; SIMÕES,CLÁUDIA M.O.; SCHENKEL,ELOIR P.. |
| Abstract: Aristolochia triangularis Cham., is one of the most frequently used medicinal plant in Southern Brazil. Preparations containing the leaves and/or stems are traditionally used as anti-inflammatory, diuretic, as well as antidote against snakebites. This study screened A. triangularis extracts, fractions and isolated compounds for different bioactivities. A weak antiproliferative activity against human lung cancer cell line (A549) was observed only for chloroform fraction obtained from stems (CFstems - CC50: 2.93 µg/mL). Also, a moderate antimicrobial activity against Staphylococcus aureus was detected just for chloroform fraction obtained from leaves (CFleaves -13-16 mm inhibition zone). Additionally, two semi-purified fractions (CFstems-4 and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aristolochia triangularis; Antiproliferative; Antiherpes; Antimicrobial; Antiprotozoal; Aristolochic acids. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500801 |
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