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Lissencephaly in a Pekingese OAK
Shimbo, Genya; Tagawa, Michihito; Oohashi, Eiji; Yanagawa, Masashi; Miyahara, Kazuro.
A 1-year-old neutered male Pekingese was presented for evaluation and further treatment of cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion was suspected following neurological examination. The dog showed signs of learning difficulty. Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex with a reduced number of gyri, as well as a cystic lesion associated with the quadrigeminal cistern. A diagnosis of lissencephaly, concurrent with a quadrigeminal cisternal cyst, was made. High-dose and multiple anticonvulsants were necessary to control the seizures. This is the first report of lissencephaly in a Pekingese. © 2017 The Japanese Society of Veterinary Science.
Palavras-chave: Lissencephaly; Magnetic resonance imaging; Pekingese.
Ano: 2017 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4564
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