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Goulart,Yara Cavalcante Fortes; Sela,Vania Ramos; Obici,Simoni; Martins,Juliana Vanessa Colombo; Otobone,Fernanda; Cortez,Diogenes Aparicio; Audi,Elisabeth Aparecida. |
The antiulcer activity of a hydro-ethanolic extract prepared from the stems of Kielmeyera coriacea Mart. (Guttiferae) was evaluated in rats employing the ethanol-acid, acute stress and Indomethacin models to induce experimental gastric ulcers. Treatment with K coriacea hydro-ethanolic extract provided significant antiulcer protection in the ethanol-acid and Indomethacin models, but not in the acute stress model. These results suggested that the K coriacea hydro-ethanolic extract increased resistance to necrotizing agents, providing a direct, protective effect on the gastric mucosa. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute stress; Anti-ulcer activity; Ethanol-acid; Indomethacin; Kielmeyera coriacea Mart. (Guttiferae). |
Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000200007 |
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