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Renal Corpuscles Were Protected From Dichlorvos: Induced Morphological Alterations in Rats by Antioxidant Vitamins International Journal of Morphology
Owoeye,Olatunde; Edem,Fabian V; Akinyoola,Bukola S; Arinola,Ganiyu O.
Dichlorvos (DDVP), an organophosphorus pesticide is a volatile compound which enters the human body through oral, dermal and inhalational routes and is excreted via the kidney. This study assessed the effects of DDVP on the histology of the kidney. Twenty five male rats (75.05 ± 5.55 g) were divided into 5 groups of 5 rats per group as follows: Unexposed group, exposure to DDVP alone for 5 weeks, and 3 other groups exposed to DDVP for 5 weeks in addition to supplement with Vitamin E, vitamin C, and red palm oil (RPO). Rats were exposed to DDVP in poorly ventilated cardboard cages for 4 hours daily. On completion of exposure, rats were euthanized and tissue processed by routine paraffin wax method and stained with H&E. Morphological alterations...
Tipo: Journal article Palavras-chave: Organophosphate; Pesticide; Glomerulus; Renal corpuscle; Vitamin- supplementation.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200017
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The Neurotoxic Effects of Artemether on the Cytoarchitecture of the Trapezoid Nuclei of Adult Male Wistar Rats (Rattus novegicus) International Journal of Morphology
Adelaja,Akinlolu Abdulazeez; Owoeye,Olatunde; Ejiwunmi,Adedayo Bewaji.
In Man, artemether is given at 160mg/kg/bodyweight for three days in the treatment of malarial. This study investigated the effects of corresponding 1.23/mg/kg/bodyweight of artemether for a period of seven days on the trapezoid nuclei and the behavioural functions on day 7 after drug administration in rats. This study observed no gross or morphological differences between the two groups of animals (control and experimental groups) on day 7 at the completion of experimental procedure. A significant statistical increase in average body weight was observed in the control groups C1 (which received only standard diet and water) and C2 (which received 1.23mg/kg/bodyweight of normal saline intramuscularly in addition to standard diet and water) from 140- +...
Tipo: Journal article Palavras-chave: Trapezoid nuclei; Neurotoxic effects; Cytoarchitecture; Rats.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500003
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