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The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats International Journal of Morphology
Turkozan,N. Y; Ulusoy,A. T; Balcioglu,H. A; Bal,F; Ozel,S.
The goal of the present study was to investigate the effects of ovariectomy and naproxen treatment on both femoral and mandibular bone mass and biomechanical competence. Sprague-Dawley rats were used and divided into five groups: baseline, sham ovariectomized, ovariectomized, sham ovariectomized + naproxen treatment, ovariectomized + naproxen treatment. Mandibles and femurs of the rats were extracted and bone mineral density of the extracted specimens were determined. The volumes and ash weights of the femurs and mandibles were estimated. Maximum loads of the femurs and mandibles were determined by using a three point bending test. Ovariectomy decreased bone mineral density of the femoral midshaft, however naproxen prevented this decrease. Neither...
Tipo: Journal article Palavras-chave: Ovariectomy; Naproxen; Bone mineral density; Maximum load.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300007
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