|
|
| OLIVEIRA,DENILSON F.; SANTOS JÚNIOR,HELVÉCIO M. DOS; NUNES,ALEXANDRO S.; CAMPOS,VICENTE P.; PINHO,RENATA S.C. DE; GAJO,GIOVANNA C.. |
| To contribute to the development of products to controlMeloidogyne exigua, the bacteria Bacillus cereus and B. subtilis were cultivated in liquid medium to produce metabolites active against this plant-parasitic nematode. Fractionation of the crude dichloromethane extracts obtained from the cultures afforded uracil, 9H-purine and dihydrouracil. All compounds were active against M. exigua, the latter being the most efficient. This substance presented a LC50 of 204 µg/mL against the nematode, while a LC50 of 260 µg/mL was observed for the commercial nematicide carbofuran. A search for protein-ligand complexes in which the ligands were structurally similar to dihydrouracil resulted in the selection of phosphoribosyltransferases, the sequences of which were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 9H-purine; Dihydrouracil; Molecular modelling; Nematicidal activity; Root-knot nematode; Uracil. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000200525 |
| |
