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	Provedor de dados Anais da ABC (AABC) (2) Autor PINTO,ANGELO C. (2) COSTA,THIAGO W.R. (1) LIMA,JOSÉLIA A. (1) MARTINEZ,SABRINA T. (1) MIRANDA,ANA LUÍSA P. (1) RIO,GABRIEL F. (1) SILVA,BÁRBARA V. (1) SILVA,LEANDRO L. (1) Mais... Palavra-chave 2-aminobenzoic acid (1) Anthranilic acid (1) Antinociception (1) Cholinergic anti-inflammatory pathway (1) Geissospermum vellosii (1) Inflammation (1) Isatin (1) Isatin oxidation (1) Pao pereira (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2015 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Antinociceptive and anti-inflammatory effects of a Geissospermum vellosii stem bark fraction Anais da ABC (AABC) LIMA,JOSÉLIA A.; COSTA,THIAGO W.R.; SILVA,LEANDRO L.; MIRANDA,ANA LUÍSA P.; PINTO,ANGELO C.. ABSTRACT Geissospermum vellosii (Pao pereira) is a Brazilian tree whose stem barks are rich in indole alkaloids that present intense anticholinesterase activity. The present study evaluated the effects of a stem bark fraction (PPAC fraction) and ethanolic extract (EE) of Pao pereira in classic murine models of inflammation and pain. The EE and PPAC fraction, both at a dose of 30 mg/kg, significantly reduced mice abdominal constriction induced by acetic acid by 34.8% and 47.5%, respectively. In the formalin test, EE (30 mg/kg) and PPAC fraction (30 and 60 mg/kg) inhibited only the second phase, by 82.8%, 84.9% and 100%, respectively. Compared with indomethacin, similar doses of EE or PPAC fraction were approximately twice as effective in causing... Tipo: Info:eu-repo/semantics/article Palavras-chave: Geissospermum vellosii; Pao pereira; Antinociception; Inflammation; Cholinergic anti-inflammatory pathway. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100237 Anthranilic acids from isatin: an efficient, versatile and environmentally friendly method Anais da ABC (AABC) RIO,GABRIEL F.; SILVA,BÁRBARA V.; MARTINEZ,SABRINA T.; PINTO,ANGELO C.. This paper describes the preparation of a series of 16 anthranilic acids in yields ranging from 51 to 97%, by treating the isatins with NaOH and H2O2. Independently of the nature of the substituent on the aromatic ring, the reactions were complete in 15 min at room temperature, whereas those of isatins containing a substituent on the nitrogen atom required longer reaction time for completion (45 min) under the same reaction conditions. Tipo: Info:eu-repo/semantics/article Palavras-chave: Isatin; Anthranilic acid; 2-aminobenzoic acid; Isatin oxidation. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000401525 Registros recuperados: 2 Primeira ... 1 ... Última

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