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PEJIĆ,SNEŽANA; TODOROVIĆ,ANA; STOJILJKOVIĆ,VESNA; GAVRILOVIĆ,LJUBICA; POPOVIĆ,NATAŠA; PAJOVIĆ,SNEŽANA B.. |
ABSTRACTUterine leiomyomas are benign soft-tissues tumors that arise from uterine smooth muscle tissue. Etiopathogenesis of leiomyomas is not well understood. We aimed to examine whether antioxidant enzyme activities and lipid hydroperoxides level in patients with leiomyoma are influenced by changes in sex hormones and gonadotropins (estradiol (E2), progesterone, FSH, and LH) during menstrual cycle and in postmenopause. The material consisted of blood and uterine tissue specimens. Hormone concentrations were determined and assays for superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activities and lipid hydroperoxides concentration were performed. In blood of examined women, a significant difference in catalase, glutathione... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant enzymes; Lipid hydroperoxides; Sex steroids; Leiomyoma. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000401771 |
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