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| Gayoso,Carla Wanderley; Lima,Edeltrudes de Oliveira; Souza,Evandro Leite de; Cechinel Filho,Valdir; Trajano,Vinícius Nogueira; Pereira,Fillipe de Oliveira; Lima,Igara Oliveira. |
| This study aimed to analyze the effectiveness of maleimides as inhibitors on the growth of fungal strains isolated from onychomycosis by the solid medium diffusion procedure. The results showed a promising antifungical activity of the assayed maleimides with formation of fungal growth inhibition halos oscillating between diameter 10 and 23mm. MIC was 100µg/mL for 3,4-dichloro-N-phenyl-methyl-maleimide and 3,4-dichloro-N-phenyl-propil-maleimide and 200µg/mL for 3,4-dichloro-N-phenyl-maleimide, 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-buthyl-maleimide. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Onychomycosis; Fungi; Maleimides; Antifungical activity. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500016 |
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| Pereira,Fillipe de Oliveira; Wanderley,Paulo Alves; Viana,Fernando Antônio Cavalcanti; Lima,Rita Baltazar de; Sousa,Frederico Barbosa de; Santos,Sócrates Golzio dos; Lima,Edeltrudes de Oliveira. |
| Trichophyton mentagrophytes is a fungus causative agent of dermatophytosis, affecting humans worldwide. This has driven the search for products for the treatment of these infections. Accordingly, the aim of this study was to investigate the antifungal activity of the Cymbopogon winterianus essential oil against T. mentagrophytes. The antifungal tests consisted of antifungal screening, determination of MIC and MFC, analysis of the essential oil's effects on mycelial growth, germination of fungal spores, fungal viability, morphogenesis, cell wall (test with sorbitol) and cell membrane (cell leakage test) of T. mentagrophytes. Upon screening, the oil inhibited all strains, with zones of growth inhibition of 24-28 mm in diameter. The MIC was 312 μg/mL and CFM... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Trichophyton mentagrophytes/mycology; Dermatophytosis Cymbopogon winterianus/essential oil; Dermatophytosis Cymbopogon winterianus/antifungal activity; Dermatophytes. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000100018 |
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| Souza,Nadábia Almeida B; Lima,Edeltrudes de Oliveira; Guedes,Diego Nunes; Pereira,Fillipe de Oliveira; Souza,Evandro Leite de; Sousa,Frederico Barbosa de. |
| This study aimed to assess the efficacy of O. vulgare L. and O. majorana L. essential oil in inhibiting the growth and survival of potentially pathogenic fungal strains and also sought to evaluate the possible mechanisms involved in the establishment of the antifungal property of the tested essential oils through assays of osmotic stability and morphogenesis. Test strains included in this study were Candida albicans ATCC 7645, C. tropicalis LM-14, C. krusei LM-09, Cryptococcus neoformans FGF-5, Aspergillus flavus LM-02, A. fumigatus IPP-21, T. rubrum ATCC 28184, T. mentagrophytes LM-64, Microsporum gypseum ATCC 184, M. canis LM-36 and Cladosporium herbarium ATCC 26362. O. vulgare essential oil presented a MIC value of 80 µL/mL, while for O. majorana this... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Essential oil; Pathogen fungi; Origanum sp/antifungal property. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300013 |
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| Gomes,Roosevelt Albuquerque; Teles,Yanna Carolina Ferreira; Pereira,Fillipe de Oliveira; Rodrigues,Luis Alberto de Sousa; Lima,Edeltrudes de Oliveira; Agra,Maria de Fátima; Souza,Maria de Fátima Vanderlei de. |
| abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and stigmasterol, sitosterol-3-O-β-D-glucopyranoside, pheophytin a, and 132-hydroxy-(132-S)-pheophytin a. Structural identification of these compounds was carried out using spectroscopic methods such as IR and 1D and 2D NMR (HOMOCOSY, HMQC, HMBC, and NOESY). Compounds isolated from S. micranthum were screened for their in vitro antifungal and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Malvaceae/phytochemistry; Sidastrum micranthum/phytochemistry; Sidastrum micranthum/antimicrobial activity/in vitro study; Pheophytins; Medicinal plants.. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400861 |
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