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| Pereira-Filho,Rose Nely; Batista,Fellipe Santos; Ribeiro,Danielle Rodrigues; Melo,Genecy Calado de; Reis,Francisco Prado; Melo,Allan Ulisses Carvalho de; Gomes,Margarete Zanardo; Cardoso,Juliana Cordeiro; Albuquerque Júnior,Ricardo Luiz Cavalcanti de. |
| The aim of this study was to assess the effect of oral administration of Hydroalcoholic Extract of Green Propolis (HEGP) on dermal carcinogenesis in rodent model. For the biological assay, we used 36 mice, assigned into 6 groups (n=6): CTR (treated with 100 mg/kg HEGP and no tumor induction), TUM (treated with water and tumor induction), GP10 (treated with 10 mg/kg HEGP and tumor induction), GP50 (treated with 50 mg/kg HEGP and tumor induction) and GP100 (treated with 100 mg/kg HEGP and tumor induction). Cancer induction was performed in the back of the mice by topical application of DMBA. After 16 weeks, mice were euthanized and their backs were submitted to post-mortem histological analysis. The mean number of lesions developed in TUM (4.14±0.89) was... |
| Tipo: Journal article |
Palavras-chave: Propolis; Skin cancer. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200024 |
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| Santana,Wagno Alcântara; Melo,Cláudia Moura de; Cardoso,Juliana Cordeiro; Pereira-Filho,Rose Nely; Rabelo,Alessandra Silva; Reis,Francisco Prado; Albuquerque-Júnior,Ricardo Luiz Cavalcanti de. |
| Achatina fulica's secretion has been recently related to antibacterial, antifungal, and cicatricial properties, and it is influenced by the kind of food offered. Therefore, this study investigated the healing potential of dressing films based on mucous secretion of Achatina fulica. Thus, surgical wounds performed in black wistar rats were dressed with films based on collagen, and on mucous secretion of A. fulica fed with Lactuca sativa; undresses worked as wounds control. After 3, 7, 14 and 21 days the animals were euthanized, and the wounds were microscopically evaluated. On the 3rd and 7th days dressing films based on mucus provided acceleration of the formation maturation of granulation tissue, better epithelization rates, and more rapid replacement of... |
| Tipo: Journal article |
Palavras-chave: Wound healing; Wound dressing; Land snails; Mucus. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200001 |
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