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| Galhardo,M.C.G.; Alvarenga,F.F.; Schueler,G.; Perez,M.; Morgado,M.G.; Ferreira,H.; Azevedo,L.M.S.; Sampaio,E.P.; Sarno,E.N.. |
| Dysregulation of the skin immune system (SIS) could explain the high prevalence of skin disorders in HIV+ individuals. The present study was carried out to determine whether alterations in the cell population of SIS and epidermal immunoactivation occur in the normal skin of HIV+ individuals. Forty-five biopsies were taken from the normal upper arm skin of 45 HIV+ patients and of 15 healthy controls. HIV+ individuals were divided into three categories according to their CD4 cell blood count (<200, 200-499 and ³500/µl). Hematoxylin-eosin was used to stain tissue sections for morphological analysis and immunohistochemistry was used for the evaluation of the frequency of macrophages, Langerhans cells, and CD lymphocyte subsets. In addition, semiquantitative... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Skin immune system; CD8 T cells; CD4-CD8 ratio; Langerhans cells. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000500017 |
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