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Morfin-Otero,Rayo; Garza-Gonzalez,Elvira; Aguirre-Diaz,Sara A.; Escobedo-Sanchez,Rodrigo; Esparza-Ahumada,Sergio; Perez-Gomez,Hector R.; Petersen-Morfin,Santiago; Gonzalez-Diaz,Esteban; Martinez-Melendez,Adrian; Rodriguez-Noriega,Eduardo. |
Abstract Background Clostridium difficile infections caused by the NAP1/B1/027 strain are more severe, difficult to treat, and frequently associated with relapses. Methods A case–control study was designed to examine a C. difficileinfection (CDI) outbreak over a 12-month period in a Mexican hospital. The diagnosis of toxigenic CDI was confirmed by real-time polymerase chain reaction, PCR (Cepheid Xpert C. difficile/Epi). Results During the study period, 288 adult patients were evaluated and 79 (27.4%) patients had confirmed CDI (PCR positive). C. difficilestrain NAP1/B1/027 was identified in 31 (39%) of the patients with confirmed CDI (240 controls were included). Significant risk factors for CDI included any underlying disease (p < 0.001), prior... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Clostridium difficile; Outbreak; 027 strain; Mexico. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000100008 |
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