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Sertié,R.A.L.; Andreotti,S.; Proença,A.R.G.; Campaña,A.B.; Lima,F.B.. |
As it is a common observation that obesity tends to occur after discontinuation of exercise, we investigated how white adipocytes isolated from the periepididymal fat of animals with interrupted physical training transport and oxidize glucose, and whether these adaptations support the weight regain seen after 4 weeks of physical detraining. Male Wistar rats (45 days old, weighing 200 g) were divided into two groups (n=10): group D (detrained), trained for 8 weeks and detrained for 4 weeks; and group S (sedentary). The physical exercise was carried out on a treadmill for 60 min/day, 5 days/week for 8 weeks, at 50-60% of the maximum running capacity. After the training protocol, adipocytes isolated from the periepididymal adipose tissue were submitted to... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Physical detraining; Adipocytes; Glucose uptake; Glucose oxidation; Lipogenesis. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000700650 |
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Proença,A.R.G.; Sertié,R.A.L.; Oliveira,A.C.; Campaãa,A.B.; Caminhotto,R.O.; Chimin,P.; Lima,F.B.. |
Numerous studies address the physiology of adipose tissue (AT). The interest surrounding the physiology of AT is primarily the result of the epidemic outburst of obesity in various contemporary societies. Briefly, the two primary metabolic activities of white AT include lipogenesis and lipolysis. Throughout the last two decades, a new model of AT physiology has emerged. Although AT was considered to be primarily an abundant energy source, it is currently considered to be a prolific producer of biologically active substances, and, consequently, is now recognized as an endocrine organ. In addition to leptin, other biologically active substances secreted by AT, generally classified as cytokines, include adiponectin, interleukin-6, tumor necrosis factor-alpha,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adipose tissue; Lipogenesis; Lipolysis; Adipogenesis; Endocrine. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000300192 |
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