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	Provedor de dados BJMBR (3) Autor Quintão,E.C.R. (3) Carvalho,M.D.T. (2) Castilho,L.N. (1) Catanozi,S. (1) Cazita,P.M. (1) Chiquito,F.C. (1) Gidlund,M. (1) Nakandakare,E.R. (1) Oliveira,H.C.F. (1) Passarelli,M. (1) Rocha,J.C. (1) Sesso,A.C. (1) Shimabukuro,A.F.M. (1) Tobias,V.E. (1) Vendrame,C.M.V. (1) Mais... Palavra-chave Atherosclerosis (2) HDL (2) Animal models (1) Aorta (1) ApoHDL (1) Cholesteryl ester transfer protein (1) Disease models (1) Emulsion (1) Fatty acid (1) Lipoproteins (1) Macrophages (1) Pathology (1) Phagocytosis (1) Triacylglycerol (1) Zymosan particles (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2010 (1) 2009 (1) 2000 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Zymosan phagocytosis by mouse peritoneal macrophages is increased by apoHDL- and not by intact HDL-covered particles BJMBR Carvalho,M.D.T.; Tobias,V.E.; Vendrame,C.M.V.; Shimabukuro,A.F.M.; Gidlund,M.; Quintão,E.C.R.. The uptake of lipids and lipoprotein particles by macrophages undergoes phagocytic activation and the formation of foam cells are key events in atherosclerosis. In this study we determined how intact high density lipoproteins (HDL) and apolipoproteins-HDL (removal of the lipid component from HDL, i.e., apoHDL) influence the phagocytosis of zymosan by mouse peritoneal macrophages. Zymosan particles preincubated together with lipoproteins or alone (control) were incubated with the macrophages. Phagocytosis activity was reported as the percent of macrophages that internalized three or more zymosan particles. HDL co-incubated with zymosan did not influence the over-all uptake of zymosan particles compared to apoHDL, which greatly enhanced the ability of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: HDL; ApoHDL; Zymosan particles; Atherosclerosis; Phagocytosis; Macrophages. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000300009 Reversible flow of cholesteryl ester between high-density lipoproteins and triacylglycerol-rich particles is modulated by the fatty acid composition and concentration of triacylglycerols BJMBR Cazita,P.M.; Castilho,L.N.; Carvalho,M.D.T.; Sesso,A.C.; Oliveira,H.C.F.; Quintão,E.C.R.. We determined the influence of fasting (FAST) and feeding (FED) on cholesteryl ester (CE) flow between high-density lipoproteins (HDL) and plasma apoB-lipoprotein and triacylglycerol (TG)-rich emulsions (EM) prepared with TG-fatty acids (FAs). TG-FAs of varying chain lengths and degrees of unsaturation were tested in the presence of a plasma fraction at d > 1.21 g/mL as the source of CE transfer protein. The transfer of CE from HDL to FED was greater than to FAST TG-rich acceptor lipoproteins, 18% and 14%, respectively. However, percent CE transfer from HDL to apoB-containing lipoproteins was similar for FED and FAST HDL. The CE transfer from HDL to EM depended on the EM TG-FA chain length. Furthermore, the chain length of the monounsaturated... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholesteryl ester transfer protein; Fatty acid; Emulsion; Triacylglycerol; HDL; Lipoproteins. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001200001 Pitfalls in the assessment of murine atherosclerosis BJMBR Catanozi,S.; Rocha,J.C.; Passarelli,M.; Chiquito,F.C.; Quintão,E.C.R.; Nakandakare,E.R.. This review provides examples of the fact that different procedures for the measurement of atherosclerosis in mice may lead to interpretation of the extent of atherosclerosis having markedly different biological and clinical significance for humans: 1) aortic cholesterol measurement is highly sensitive for the detection of early and advanced atherosclerosis lesions, but misses the identification of the location and complexity of these lesions that are so critical for humans; 2) the histological analysis of the aortic root lesions in simvastatin-treated and control mice reveals similar lesion morphology in spite of the remarkable simvastatin-induced reduction of the aortic cholesteryl ester content; 3) in histological analyses, chemical fixation and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Atherosclerosis; Animal models; Disease models; Aorta; Pathology. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600001 Registros recuperados: 3 Primeira ... 1 ... Última

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