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RAMIREZ,BEATRIZ U; RETAMAL,LEIRA; VERGARA,CECILIA. |
The well-established trophic role of CNTF upon neurons led to performing clinical trials in patients of neurodegenerative diseases. However, trials were suspended due to side effects such as severe weight loss, hyperalgesia, coughing, muscle cramps and pain. So far it is not known how CNTF triggers the problems related to skeletal muscle cramps and pain. CNTF has also been described as a myotrophic factor for denervated skeletal muscles, but the possibility that it affects innervated muscles has also been considered. Since a myotrophic factor could be a valuable tool for treatment of several muscle diseases, we studied the effects of low doses of CNTF delivered systemically by an osmotic pump, over the electrical and mechanical properties of innervated and... |
Tipo: Journal article |
Palavras-chave: CNTF; Contraction and relaxation time; Denervation; EMG; Fibrillation; Skeletal muscle. |
Ano: 2003 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602003000300003 |
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MONTECINO,VIVIAN; MOLINA,XIMENA; MARTÏNEZ,GINGER; OLMEDO,M. ISABEL; RETAMAL,LEIRA; HANNACH,GABRIELA; ORELLANA,MÓNICA V.. |
Marine microalgae exposed to ultraviolet radiation (UV) have complex adaptive responses provided by a series of protection and repair mechanisms. Interspecific differences in UV sensibility could result in differential selection of the more tolerant species, having consequences for the structure of phytoplankton assemblages. The relative importance of protection and photorepair mechanisms of microalgal cells exposed to potential UV-B stress was studied in monocultures with different taxonomic, ecological and size characteristics obtained from the Chilean coast. Differences in photosynthesis and growth rates were predicted, since the ability to effectively acclimate to UV is not universal between microalgal species. The dinoflagellate Alexandrium catenella... |
Tipo: Journal article |
Palavras-chave: Photosynthesis; Absorbance; Photoreactivation; Growth; UV response. |
Ano: 2001 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2001000200007 |
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