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| OLIVEIRA,FLAVIA DE; MAIFRINO,LAURA B.M.; JESUS,GUSTAVO P.P. DE; CARVALHO,JULIANA G.; MARCHON,CLÁUDIA; RIBEIRO,DANIEL A.. |
| Estrogen deprivation in postmenopausal women increases cardiovascular risk. Cardiovascular risk as a result of atherosclerosis is able to induce an inflammatory disease as far as cyclooxygenase-2 ( COX-2) expression. The purpose of the study was to investigate the role of COX-2 on exercise training in female mice low-density lipoprotein receptor knockout ( LDL-KO) with or without ovariectomy. A total of 15 female C57BL/6 mice and 15 female LDL-KO mice were distributed into 6 groups: sedentary control, sedentary control ovariectomized, trained control ovariectomized, LDL-KO sedentary, LDL-KO sedentary ovariectomized and LDL-KO trained ovariectomized. The ascending part of the aorta was stained with H&E and COX-2 expression was assessed by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Atherosclerosis; Ciclooxygenase-2; Exercise; Menopause. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000301157 |
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