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| Antunes,S.L.G.; Chimelli,L.M.; Rabello,E.T.; Valentim,V.C.; Corte-Real,S.; Sarno,E.N.; Jardim,M.R.. |
| The nerve biopsies of 11 patients with pure neuritic leprosy were submitted to routine diagnostic procedures and immunoperoxidase staining with antibodies against axonal (neurofilament, nerve growth factor receptor (NGFr), and protein gene product (PGP) 9.5) and Schwann cell (myelin basic protein, S-100 protein, and NGFr) markers. Two pairs of non-adjacent histological cross-sections of the peripheral nerve were removed for quantification. All the fascicles of the nerve were examined with a 10X-ocular and 40X-objective lens. The immunohistochemistry results were compared to the results of semithin section analysis and clinical and electroneuromyographic data. Neurofilament staining was reduced in 100% of the neuritic biopsies. NGFr positivity was also... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neurofilament protein; Nerve growth factor receptor; S-100 protein; Myelin basic protein; Gene product 9.5; Neuritic leprosy; Peripheral neuropathy. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000800010 |
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