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Pejić,Sneana; Todorović,Ana; Stojiljković,Vesna; Cvetković,Dragana; Lučić,Nenad; Radojičić,Ratko M.; Saičić,Zorica S.; Pajovic,Sneana B.. |
Epidemiological and experimental data point to involvement of oxygen derived radicals in the pathogenesis of gynecological disorders, as well as in cancer development. The objective of the present study was to examine changes in activities and levels of copper/zinc superoxide dismutase (CuZnSOD) and lipid hydroperoxides (LOOH) in blood and endometrial tissue of patients diagnosed with uterine myoma, endometrial polypus, hyperplasia simplex, hyperplasia complex and adenocarcinoma endometrii. The results of our study have shown decreased SOD activities and unchanged SOD protein level in blood of all examined patients in comparison to healthy subjects. Decrease of both SOD activity and level was found in endometrium of patients with hyperplasia simplex,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Copper/zinc superoxide dismutase; Lipid hydroperoxides; Uterine myoma; Endometrial polypus; Endometrial hyperplasia; Endometrial adenocarcinoma. |
Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000300011 |
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