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| Raja,Sadaf Azad; Abbas,Seher; Shah,Syed Tahir Abbas; Tariq,Aamira; Bibi,Nazia; Yousuf,Arzu; Khawaja,Athar; Nawaz,Muhammad; Mehmood,Arshad; Khan,Muhammad Jadoon; Hussain,Alamdar. |
| Abstract Gene expression is tightly regulated in time and space through a multitude of factors consisting of signaling molecules. Soluble N-ethylmaleimide-sensitive-factor attachment protein receptors (SNARE) are membrane proteins responsible for the intercellular trafficking of signals through endocytosis and exocytosis of vesicles. Altered expression of SNARE proteins in cellular communication is the major hallmark of cancer phenotypes as indicated in recent studies. SNAREs play an important role in maintaining cell growth and epithelial membrane permeability of the bladder and are not only involved in cancer progression but also metastatic cell invasion through SNARE-mediated trafficking. Synaptobrevin2/Vesicle associated membrane protein-2 (v-SNARE)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: SNARE; Bladder cancer; Vesicle fusion; Gene expression. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000100040 |
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