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Rakesh Sharma; Rakesh K. Tandon. |
Lithogenic diet, casein and apple fiber diets were fed to hamsters for 3-5 weeks. For control group, animals were fed on normal Purina chow without any supplement. The cholesterol lowering effect of lithogenic diet, casein and apple diets were compared. After dietary regimen, animals were screened for any gall stone formation. The isolated liver microsomes were separated from animals and tested for the cholesterol-7α Hydroxylase (CH) enzyme activity measurement in all three groups. The control animals did not show any gall stone formation and their CH enzyme activities were normal. The lithogenic diet showed significantly enhanced CH enzyme activities while animals fed on casein and apple diet regimen showed moderate increase in microsomal CH... |
Tipo: Manuscript |
Palavras-chave: Molecular Cell Biology. |
Ano: 2010 |
URL: http://precedings.nature.com/documents/4205/version/1 |
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Rakesh Sharma; Soonjo Kwon; R Baktur; Avdhesh Sharma. |
Carbon Nanotube (CNT) materials have superior properties in electric current carrying capacity, thermal conductivity, and thermal stability. Due to their structure with high aspect ratio, they have structural unusual toxicity and complicate safety issue in a target tissue. In optimized quantities with limited functionality, special type of CNT assembly such as “buckyball” can be used as a potential drug carrier of bioactive molecules and display with increased circulating time and acceptable functionality. We analyzed cytoxicity and inflammatory response following exposure of different size, mass, shape, and functionality of CNTs. We monitored the transport across skin, physiological perturbation of transepithelial electrical... |
Tipo: Presentation |
Palavras-chave: Biotechnology. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3948/version/1 |
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