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	Provedor de dados BJPS (2) Autor Rao,Nali Sreenivasa (2) Srikanth,Meka Venkata (2) Sunil,Songa Ambedkar (2) Balaji,Sakamuri (1) Kumar,Kommana Srinivas Phani (1) Murthy,Kolapalli Venkata Ramana (1) Murthy,Kolaplli Venkata Ramana (1) Uhumwangho,Michael Uwumagbe (1) Mais... Palavra-chave Bilayered tablet/biphasic release (1) Chronotherapeutic drug/delivery systems (1) Compression coated tablets (1) Drugs/controlled release (1) Hydrophilic polymers/drug release (1) Hydrophilic polymers/use (1) Lornoxicam/bilayered tablet (1) Lornoxicam/development (1) Polyethylene Oxides (1) Predetermined lag time (1) Torsemide (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (1) 2011 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Development and evaluation of a chronotherapeutic drug delivery system of torsemide BJPS Sunil,Songa Ambedkar; Rao,Nali Sreenivasa; Srikanth,Meka Venkata; Uhumwangho,Michael Uwumagbe; Kumar,Kommana Srinivas Phani; Murthy,Kolaplli Venkata Ramana. The objective of this study was to prepare and evaluate chronotherapeutic drug delivery systems (ChrDDs) of torsemide. Compression coated tablets (CCT) containing torsemide in the core tablet were prepared by the compression coating technique with different grades of polyethylene oxide (PEO WSR 301 &amp; 1105). The optimized formulations were characterised for tabletting parameters and drug polymer interaction by Fourier-Transform Infrared Spectroscopy (FTIR).The hardness of all the CCT using PEO WSR 301 &amp; PEO WSR 1105 were in the range 6-8 kg/cm² &amp; 5.5 to 7 kg/cm² respectively. Their friability values were <0.3%. All the CCT showed a clear lag time but finalized as per the predetermined lag time. As the amount of PEO was increased... Tipo: Info:eu-repo/semantics/article Palavras-chave: Torsemide; Chronotherapeutic drug/delivery systems; Polyethylene Oxides; Compression coated tablets; Predetermined lag time. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300017 Design and evaluation of lornoxicam bilayered tablets for biphasic release BJPS Sunil,Songa Ambedkar; Srikanth,Meka Venkata; Rao,Nali Sreenivasa; Balaji,Sakamuri; Murthy,Kolapalli Venkata Ramana. The objective of the present investigation was to develop bilayered tablets of lornoxicam to achieve biphasic release pattern. A bilayered tablet, consisting of an immediate and controlled release layer, was prepared by direct compression technique. The controlled release effect was achieved by using various hydrophilic natural, semi synthetic and synthetic controlled release polymers such as xanthan gum, hydroxypropyl methylcellulose (HPMC) and polyethylene oxide (PEO) to modulate the release of the drug. The in vitro drug release profiles showed the biphasic release behavior in which the immediate release (IR) layer containing the lornoxicam was released within 15 minutes, whereas the controlled release (CR) layer controlled the drug release for up to 24... Tipo: Info:eu-repo/semantics/article Palavras-chave: Lornoxicam/bilayered tablet; Lornoxicam/development; Bilayered tablet/biphasic release; Hydrophilic polymers/use; Hydrophilic polymers/drug release; Drugs/controlled release. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000400004 Registros recuperados: 2 Primeira ... 1 ... Última

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