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| Sousa,Letícia Pinheiro de; Silva,Annelisa Farah da; Calil,Natalia Oliveira; Oliveira,Murilo Gomes; Silva,Silvio Silvério da; Raposo,Nádia Rezende Barbosa. |
| This study evaluated, in vitro, the antimicrobial activity and the anti-adherent property of xylitol (0.5, 2.5 and 5.0%, w/v) on two Pseudomonas aeruginosa strains (ATCC 9027 and clinical). The assay of antimicrobial activity was performed to determine a minimum inhibitory concentration (MIC) and the adhesion test was performed, by which the parameters regarding, growth in the culture medium, number of colony forming units (CFUs) released and slide evaluation by scanning electron microscopy (SEM) were analyzed. The Statistical Package for the Social Sciences (SPSS) was employed for statistical analysis. Results showed that xylitol had no antimicrobial activity on these strains; however, the inhibition of bacterial adherence was observed in microphotographs... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bacterial adhesion; Pseudomonas aeruginosa; Prevention and control; Xylitol. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000500004 |
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| Caneschi,César Augusto; Almeida,Angelina Maria de; Martins,Francislene Juliana; Hyaric,Mireille Le; Oliveira,Manoel Marques Evangelista; Macedo,Gilson Costa; Almeida,Mauro Vieira de; Raposo,Nádia Rezende Barbosa. |
| Abstract Onychomycosis is a fungal infection of the nail caused by high densities of filamentous fungi and yeasts. Treatment for this illness is long-term, and recurrences are frequently detected. This study evaluated in vitro antifungal activities of 12 organic compounds derived from amino alcohols against standard fungal strains, such as Trichophyton rubrum CCT 5507 URM 1666, Trichophyton mentagrophytes ATCC 11481, and Candida albicans ATCC 10231. The antifungal compounds were synthesized from p-hydroxybenzaldehyde (4a-4f) and p-hydroxybenzoic acid (9a-9f). Minimum inhibitory concentrations and minimum fungicidal concentrations were determined according to Clinical and Laboratory Standards Institute protocols M38-A2, M27-A3, and M27-S4. The amine series... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amino alcohols; Amides; Lipophilicity; Antifungal activity; Onychomycosis. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300476 |
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| Teixeira,Raquel da Silva; Rocha,Paula Rafaela; Polonini,Hudson Caetano; Brandão,Marcos Antônio Fernandes; Chaves,Maria das Graças Afonso Miranda; Raposo,Nádia Rezende Barbosa. |
| In order to treat hyperpigmentation-related problems, there has been a global trend in developing cosmetics claiming to have skin-whitening properties, which act by inhibiting melanin biosynthesis. The objective of this work was to evaluate the in vitro mushroom tyrosinase inhibitory activity of five Amazonian native flora oils, and so to verify the possibility of their incorporation into cosmetic products. In addition, the fatty acid composition of the essential oils was determined by gas chromatography-flame ionisation detection in order to determine the main components of these oils. The tyrosinase inhibitory activity of the tested oils was found to be in the following order: açaí (IA50 = 66.08 µg mL-1) > tucumã > patauá > pracaxi > castanha... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amazonian plants/evaluation; Amazonian plants/dermatological use; Skin lightening agents; Tyrosinase/inhibition; Tyrosinase/in vitro evaluation; Melanin; Hyperpigmentation/treatment. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300006 |
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