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The Cytoplasm Affects the Epigenome in Drosophila melanogaster ArchiMer
Grunau, Christoph; Voigt, Susanne; Dobler, Ralph; Dowling, Damian K.; Reinhardt, Klaus.
Cytoplasmic components and their interactions with the nuclear genome may mediate patterns of phenotypic expression to form a joint inheritance system. However, proximate mechanisms underpinning these interactions remain elusive. To independently assess nuclear genetic and epigenetic cytoplasmic effects, we created a full-factorial design in which representative cytoplasms and nuclear backgrounds from each of two geographically disjunct populations of Drosophila melanogaster were matched together in all four possible combinations. To capture slowly-accumulating epimutations in addition to immediately occurring ones, these constructed populations were examined one year later. We found the K4 methylation of histone H3, H3K4me3, an epigenetic marker...
Tipo: Text Palavras-chave: Epigenetics; Mitochondria; Mito-nuclear coevolution; Wolbachia.
Ano: 2018 URL: https://archimer.ifremer.fr/doc/00478/58935/62427.pdf
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