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Pseudorabies virus can be classified into five genotypes using partial sequences of UL44 BJM
Fonseca Jr.,A. A.; Camargos,M. F.; Sales,M. L.; Heinemann,M. B.; Leite,R.C.; Reis,J. K. P..
Suid herpesvirus 1 (SuHV-1) is the causative agent of pseudorabies (PR), a disease of great importance due to the huge losses it causes in the swine industry. The aim of this study was to determine a method for genotyping SuHV-1 based on partial sequences of the gene coding for glycoprotein C (gC) and to elucidate the possible reasons for the variability of this region. A total of 109 gCsequences collected from GenBank were divided into five major groups after reconstruction of a phylogenetic tree by Bayesian inference. The analysis showed that a portion of gC (approximately 671 bp) is under selective pressure at various points that coincide with regions of protein disorder. It was also possible to divide SuHV-1 into five genotypes that evolved under...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudorabies; Glycoprotein; Bioinformatics.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400048
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