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	Provedor de dados BJM (1) Genet. Mol. Biol. (1) Autor Reis,Mitermayer Galvão dos (2) Costa,Federico (1) Dourado,Marcos Vinícius (1) Figueira,Cláudio Pereira (1) Gonçalves,Marilda Souza (1) Moura Neto,José Pereira de (1) Ristow,Paula (1) Santos,Ana Amélia Nunes (1) Mais... Palavra-chave G6PD mutations (1) Glucose-6-phosphate dehydrogenase deficiency (1) Leptospira interrogans (1) Natural reservoirs (1) Neonatal screening (1) Rattus norvegicus (1) Renal colonization (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2015 (1) 2008 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Heterogenic colonization patterns by Leptospira interrogans in Rattus norvegicus from urban slums BJM Santos,Ana Amélia Nunes; Figueira,Cláudio Pereira; Reis,Mitermayer Galvão dos; Costa,Federico; Ristow,Paula. Abstract We evaluated the renal colonization by Leptospira interrogans in Rattus norvegicus (rats), as it is the major natural reservoir of urban leptospirosis. We caught 72 R. norvegicus, out of which 32 were found to be positive for L. interrogans by immunofluorescence assay. From these rats, we selected 17 and divided them into six groups based on the mass-age/sex. We performed the immunohistochemistry test against L. interrogans in the kidney sections of the rats and systematically counted the colonized tubules (CTs) in 20 fields. The proportion of positive fields varied from 5% to 95%. The number of CTs in 20 fields varied from 0.5 to 85.5. These differences were not related to age or sex of the animals. The characterization of leptospiral... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospira interrogans; Renal colonization; Natural reservoirs; Rattus norvegicus. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401161 A novel c.197T ® A variant among Brazilian neonates with glucose-6-phosphate dehydrogenase deficiency Genet. Mol. Biol. Moura Neto,José Pereira de; Dourado,Marcos Vinícius; Reis,Mitermayer Galvão dos; Gonçalves,Marilda Souza. Glucose-6-phosphate dehydrogenase (G6PD, EC 1.1.1.49) deficiency is the most common enzyme deficiency worldwide, causing a spectrum of diseases including neonatal hyperbilirubinemia and acute or chronic hemolysis. We used the methemoglobin reduction test and G6PD electrophoresis to screen 655 neonates (354 females and 301 males) for common G6PD mutations in the city of Salvador in the Northeastern Brazilian state Bahia and found that 66 (10.1%) were G6PD-deficient (41 females and 25 males). The 66 (10.1%) G6PD-deficient neonates were assessed for the c.376 A -> G (exon 5) and c.202 G -> A (exon 4) mutations using the polymerase chain reaction and restriction enzyme fragment length polymorphism (PCR-RFLP) analysis and the results validated by DNA... Tipo: Info:eu-repo/semantics/other Palavras-chave: Glucose-6-phosphate dehydrogenase deficiency; G6PD mutations; Neonatal screening. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000100006 Registros recuperados: 2 Primeira ... 1 ... Última

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