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	Provedor de dados International Journal of Morphology (2) Autor Rengifo,Aura Caterine (2) Torres-Fernández,Orlando (2) Garzón,Mary Janeth (1) Hurtado,Andrea P (1) Umbarila,Vanessa Jazmin (1) Palavra-chave Cerebral cortex (2) Immunohistochemistry (2) MAP-2 (1) Mouse (1) NeuN (1) Neurons (1) Pyramidal neurons (1) Rabies (1) Rabies virus (1) Mais... Tipo do documento Journal article (2) Ano 2016 (1) 2015 (1) País Chile (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Differential Effect of the Route of Inoculation of Rabies Virus on NeuN Immunoreactivity in the Cerebral Cortex of Mice International Journal of Morphology Rengifo,Aura Caterine; Umbarila,Vanessa Jazmin; Garzón,Mary Janeth; Torres-Fernández,Orlando. Rabies is a lethal disease caused by a neurotropic virus that produces inconspicuous morphological changes hardly observable with conventional histopathology. The fatal outcome caused by rabies could be attributed to specific biochemical changes that severely impact neuronal function. The neuronal nuclear protein (NeuN) has become a widely used neuronal marker for the research and the histopathological diagnosis of nervous system diseases. To evaluate the distribution of the protein NeuN in the motor cortex of normal and rabies-infected mice adult ICR mice were inoculated with rabies virus either intramuscularly or intracerebrally. Rabies-infected mice were sacrificed at the terminal stage of the disease. Control mice were also euthanized at the same age.... Tipo: Journal article Palavras-chave: Rabies; NeuN; Cerebral cortex; Mouse; Immunohistochemistry; Neurons. Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000400031 Immunohistochemical Overexpression of MAP-2 in the Cerebral Cortex of Rabies-Infected Mice International Journal of Morphology Hurtado,Andrea P; Rengifo,Aura Caterine; Torres-Fernández,Orlando. The microtubule-associated protein MAP-2 is an integral part of the cytoskeleton and plays an important role in neural morphogenesis. This protein is an essential component of the dendritic cytoskeleton, especially in the adult brain, and its expression can be altered under experimental or pathological conditions. The purpose of this study was to evaluate the effect of infection with the rabies virus on MAP-2 immunoreactivity in the cerebral cortex of mice. The mice were inoculated with the rabies virus and the animals were sacrificed when the disease reached its advanced stage, together with uninfected animals of the same age. The brains were extracted after being previously perfusion-fixed with paraformaldehyde; coronal sections were obtained with a... Tipo: Journal article Palavras-chave: MAP-2; Cerebral cortex; Pyramidal neurons; Rabies virus; Immunohistochemistry. Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200010 Registros recuperados: 2 Primeira ... 1 ... Última

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