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Genetic and environmental influences on blood pressure and physical activity: a study of nuclear families from Muzambinho, Brazil BJMBR
Forjaz,C.L.M.; Bartholomeu,T.; Rezende,J.A.S.; Oliveira,J.A.; Basso,L.; Tani,G.; Prista,A.; Maia,J.A.R..
Blood pressure (BP) and physical activity (PA) levels are inversely associated. Since genetic factors account for the observed variation in each of these traits, it is possible that part of their association may be related to common genetic and/or environmental influences. Thus, this study was designed to estimate the genetic and environmental correlations of BP and PA phenotypes in nuclear families from Muzambinho, Brazil. Families including 236 offspring (6 to 24 years) and their 82 fathers and 122 mothers (24 to 65 years) were evaluated. BP was measured, and total PA (TPA) was assessed by an interview (commuting, occupational, leisure time, and school time PA). Quantitative genetic modeling was used to estimate maximal heritability (h²), and genetic and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Exercise; Hypertension; Environmental influence; Heritability; Genetic epidemiology.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200023
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